Blood Flow in the Calf Muscle During Walking Studied by the Xenon - 133 Clearance Method

نویسندگان

  • JOSEPH S. ALPERT
  • NIELS A. LASSEN
چکیده

Nineteen patients with obliterative arteriosclerotic disease of the legs and suffering from intermittent claudication were studied before and during a 6 months' training program. The maximal walking distance and the calf muscle blood flow during walking (xenon-133 clearance technique) was recorded at monthly intervals. A significant correlation was established between improvement in maximal walking distance and a change on exercise toward more normal (that is, more adequate) blood flow in the calf. In particular, it was found that calf muscle blood flow during walking was increased by physical training. The data suggest that functional factors (for example, better coordination of the working muscles or a decrease of in-between-step intramuscular pressure) as well as anatomic factors (increase in number or diameter of collateral vessels, or both) are involved in increasing collateral efficiency.

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Exercise and intermittent claudication. Blood flow in the calf muscle during walking studied by the xenon-133 clearance method.

Nineteen patients with obliterative arteriosclerotic disease of the legs and suffering from intermittent claudication were studied before and during a 6 months' training program. The maximal walking distance and the calf muscle blood flow during walking (xenon-133 clearance technique) was recorded at monthly intervals. A significant correlation was established between improvement in maximal wal...

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Exercise and Intermittent Claudication

Nineteen patients with obliterative arteriosclerotic disease of the legs and suffering from intermittent claudication were studied before and during a 6 months' training program. The maximal walking distance and the calf muscle blood flow during walking (xenon-133 clearance technique) was recorded at monthly intervals. A significant correlation was established between improvement in maximal wal...

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Validity of the Xenon-133-method for Measurement of Muscle Blood Flow Evaluated by Simultaneous Venous Occlusion Plethysmography: Observations in the Calf of Normal Man and in Patients with Occlusive Vascular Disease.

• Intramuscular injection of a small volume of saline containing radioactive, sodium (Na*) was used by Kety for assessing local muscle blood flow. With Xe", a radioactive isotope of the lipophilic inert gas xenon, diffusion equilibrium is better maintained than with the hydrophilic Na* ions, and Xe" clearance studies allow the estimation of local muscle blood flow per unit weight of muscle, e.g...

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تاریخ انتشار 2005